Antioxidant Activity of Combination Simplicia and Extract of Avocado Peel (Persea americana Mill.) and Lime Peel (Citrus aurantifolia)
DOI:
https://doi.org/10.25026/jtpc.v8i2.440Keywords:
Antioxidant, Avocado peel, Lime peel, IC50, DPPHAbstract
The avocado peel (Persea americana Mill.) and lime peel (Citrus aurantifolia) are biodegradable waste materials that contain antioxidant activities. This study aims to determine the antioxidant activities of avocado peel and lime peel extracts on their single and combined form. Samples were extracted with the maceration method using 96% ethanol solvent, then an antioxidant activity test towards DPPH (2,2-diphenyl-1-picrylhydrazyl) radical inhibition measured using the UV-Vis spectrophotometer. This research showed that the antioxidant activities obtained with the value of IC50 (inhibition concentration) are at 24.82 ppm from the avocado peel extract, 131.12 ppm from lime peel extract, and also from the simplicia combination with the ratio of 1:1; 1:2; and 2:1 are respectively at 45.01 ppm, 87.41 ppm; and 38.49 ppm, meanwhile on the combined extracts with the ratio of 1:1; 1:2; and 2:1 are respectively at 31.16 ppm; 39.28 ppm; and 11.69 ppm and followed by ascorbic acid at 4.35 ppm.
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References
[1] Yuslianti, E. R., 2018. Pengantar Radikal Bebas dan Antioksidan. Yogyakarta: Deepublish.
[2] Hani, R. C., & Milanda T., 2018. Review: Manfaat Antioksidan Pada Tanaman Buah di Indonesia. Farmaka, 14(1), 184-190
[3] Santoso, U., 2017. Antioksidan Pangan. Yogyakarta: Gadjah Mada University Press
[4] Khasanah, I., Ulfah M., &Sumantri., 2014. Uji Aktivitas Antioksidan Ekstrak Etanolik Kulit Buah Jeruk Nipis (Citrus aurantifolia) Dengan Metode DPPH (1,1-difenil-2-pikrilhidrazil). Jurnal Ilmu Farmasi dan Farmasi Klinik, 11(2), 9-17
[5] Siyanti, A., Fitriani, N., &Angga., 2019. Uji Aktivitas Antioksidan Ekstrak Etanol Kulit Alpukat (Persea americana Mill.) terhadap Peredaman DPPH. Proceeding of Mulawarman Pharmaceuticals Conferences, 10(1), 72–75. https://doi.org/10.25026/mpc.v10i1.357
[6] Wulandari, G., Abdul Rahman, A., Rubiyanti, R., 2019. Uji Aktivitas Antibakteri Ekstrak Etanol Kulit Buah Alpukat (Persea americana Mill) Terhadap Staphylococcus aureus ATCC 25923. Media Informasi 15(1), 74-80
[7] Firlia., & Hastuti, S., 2020. Determination Of Total Flavonoid Levels On Alpukat Fruit Peel (Persea americana Mill.). Media Eksakta, 16(2), 128–133.
[8] Ulfa, A. M., Marcellia, S., & Rositasari, E., 2020. Efektivitas Formulasi Krim Ekstrak Kulit Jeruk Nipis (Citrus aurantifolia-pericappium) Sebagai Pengobatan Luka Sayat Stadium II Pada Tikus Putih(Rattus novergicus) Galur Wistar. Jurnal Farmasi Malahayati3(1), 42-52
[9] Hilal, N., Syahrir, A., Mochamad Afendi, F., Susetyo, B., Mochamad, F., & Program, A., 2016. Efek Sinergis Bahan Aktif Tanaman Obat Berbasiskan Jejaring Dengan Protein Target. Jurnal Jamu Indonesia 1(1), 35-46
[10] Molyneux, P., 2004. The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity. Journal of Science Technology, 26(2), 211-219
[11] Karim, K., Jura, M. R., & Sabang, S. R., 2015. Uji Aktivitas Antioksidan Ekstrak Daun Patikan Kebo (Euphorbia hirta L.). Jurnal Akademika Kimia 4(2), 56-63
[12] Putranti, W., Witasari, H. A., & Fajria, N. K., 2021. Efek Sinergis Ekstrak Etanol Daun Sirih (Piper betle L.) dan Bawang Putih (Allium sativum) Terhadap Candida albicans. Jurnal Ilmiah Apoteker Indonesia (JIAI), 1(1), 11-16
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