Formulation and Stability Tests of Hair Tonic from Oil Palm (Elaeis guineensis Jacq.) Leaves Extract and Effectiveness in Protecting Hair
DOI:
https://doi.org/10.25026/jtpc.v6i2.524Keywords:
Oil Palm Leaf, Hair Tonic, Antioxidant, IC50, EffectivenessAbstract
Hair loss is a condition that unavoidable process, where the hair is detached more than 100 strands per day that occurs continuously. Oil palm leaf with their compounds can be used to treat hair loss and damage. The purpose of this study was to formulate oil palm leaf extract into hair tonic preparations and evaluate the effectiveness in preventing hair damage. Hair tonic formula from oil palm leaf extract contains 96% ethanol, menthol, propylene glycol, phenoxyethanol, and aquades. The evaluation of hair tonic preparations included organoleptic, homogeneity, pH, and viscosity tests, as well as tests of antioxidant activity and effectiveness of hair tonic preparations. The results of the antioxidant activity test of oil palm leaf extract hair tonic showed the IC50 value at room temperature (25°C) indicating an average value of 37.2519±8.535 ppm, warm temperature (50°C) 40.5459±9.086 ppm, and cold temperature (4°C) 36.8257±6.928 ppm, which belongs to the category of very strong antioxidant activity, with the results of the evaluation of the oil palm leaf hair tonic slightly colored. greenish to dark green, has a distinctive menthol aroma, has a pH and viscosity that meets the requirements of a good hair tonic preparation, with pH between 3-7 and viscosity less than 5 cPs. Hair tonic preparations of oil palm leaf extract can prevent hair decolorization due to sun exposure at concentrations of 25 ppm to 200 ppm.Downloads
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References
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[22] T. Prasertpol and W. Tiyaboonchai. 2020. Nanostructured lipid carriers: A novel hair protective product preventing hair damage and discoloration from UV radiation and thermal treatment, J. Photochem. Photobiol. B, vol. 204, p. 111769, doi: 10.1016/j.jphotobiol.2019.111769.
[2] E. Fernández, B. Martínez-Teipel, R. Armengol, C. Barba, and L. Coderch. 2012. Efficacy of antioxidants in human hair, J. Photochem. Photobiol. B, vol. 117, pp. 146–156, doi: 10.1016/j.jphotobiol.2012.09.009.
[3] M. A. Umborowati. 2012. Rambut Rontok Akibat Lingkungan dan Kosmetik, Berk. Ilmu Kesehat. Kulit Dan Kelamin, vol. 24, no. 1, p. 8.
[4] S. Indriaty, T. Indrawati, and S. Taurhesia. 2018. Formulation and test activities of hair tonic with a combination of the aqueous extracts of aloe vera (Aloe vera L.) and licorice (Glycyrrhiza glabra L.), Pharmaciana, vol. 8, no. 1, p. 33, doi: 10.12928/pharmaciana.v8i1.8877.
[5] A. Andoko and Widodoro. 2013. Berkebun Kelapa Sawit “Si Emas Cair.” AgroMedia,
[6] Che Zain, Lee, Teo, and Shaari. 2020. Adsorption and Desorption Properties of Total Flavonoids from Oil Palm (Elaeis guineensis Jacq.) Mature Leaf on Macroporous Adsorption Resins, Molecules, vol. 25, no. 4, p. 778, doi: 10.3390/molecules25040778.
[7] N. Z. Yusof. 2016. Potential Uses of Oil Palm (Elaeis Guineensis) Leaf Extract in Topical Application, J. Oil Palm Res., vol. 28, no. 4, pp. 520–530, doi: 10.21894/jopr.2016.2804.13.
[8] A. R. M. Syahmi et al. 2010. Acute Oral Toxicity and Brine Shrimp Lethality of Elaeis guineensis Jacq., (Oil Palm Leaf) Methanol Extract, Molecules, vol. 15, no. 11, pp. 8111–8121, doi: 10.3390/molecules15118111.
[9] N. Z. Yusof, S. S. Abd Gani, Z. A. Azizul Hasan, and Z. Idris. 2018. Skin and Eye Irritation Assessment of Oil Palm (Elaeis guineensis) Leaf Extract for Topical Application, Int. J. Toxicol., vol. 37, no. 4, pp. 335–343, doi: 10.1177/1091581818773979.
[10] I. Sunnah, A. R. Erwiyani, M. S. Aprilliani, M. Maryanti, and G. A. Pramana. 2021. Aktivitas Antihiperurisemia dan Evaluasi Sifat Fisik Sediaan Sirup Ekstrak Labu Kuning (Cucurbita maxima), Indones. J. Pharm. Nat. Prod., vol. 4, no. 1, doi: 10.35473/ijpnp.v4i1.973.
[11] N. S. Yin, S. Abdullah, and C. K. Phin. 2013. Phytochemical Constituents from Leaves of Elaeis Guineensis and Their Antioxidant and Antimicrobial Activities, Int. J. Pharm. Pharm. Sci., vol. 5, p. 4.
[12] P. Molyneux. 2004. The use of the stable free radical diphenylpicryl- hydrazyl (DPPH) for estimating antioxidant activity, Songklanakarin J. Sci. Technol., vol. 26, no. 2, p. 9.
[13] N. Francenia Santos-Sánchez, R. Salas-Coronado, C. Villanueva-Cañongo, and B. Hernández-Carlos. 2019. Antioxidant Compounds and Their Antioxidant Mechanism, in Antioxidants, E. Shalaby, Ed. IntechOpen. doi: 10.5772/intechopen.85270.
[14] Che Zain, Lee, Teo, and Shaari. 2020. Adsorption and Desorption Properties of Total Flavonoids from Oil Palm (Elaeis guineensis Jacq.) Mature Leaf on Macroporous Adsorption Resins, Molecules, vol. 25, no. 4, p. 778, doi: 10.3390/molecules25040778.
[15] S. Indriaty, T. Indrawati, and S. Taurhesia. 2018. Formulation and test activities of hair tonic with a combination of the aqueous extracts of aloe vera (Aloe vera L.) and licorice (Glycyrrhiza glabra L.), Pharmaciana, vol. 8, no. 1, p. 33, doi: 10.12928/pharmaciana.v8i1.8877.
[16] R. C. Rowe, P. J. Sheskey, and M. E. Quinn. 2009. Handbook of pharmaceutical excipients, 6th ed. London: Pharmaceutical press.
[17] L. Leny, K. Fitri, Y. K. Lase, I. Hafiz, and B. Iskandar. 2022. Formulation of Hair Tonic from Ethanol Extract of Sea Hibiscus (Hibiscus tileaceus L.) Leaves in Promoting Hair Growth on Guinea Pig (Cavia porcellus), J. Drug Deliv. Ther., vol. 12, no. 2, pp. 1–5, doi: 10.22270/jddt.v12i2.5364.
[18] C. Surber, P. Humbert, C. Abels, and H. Maibach. 2018. The Acid Mantle: A Myth or an Essential Part of Skin Health? in Current Problems in Dermatology, vol. 54, C. Surber, C. Abels, and H. Maibach, Eds. S. Karger AG, pp. 1–10. doi: 10.1159/000489512.
[19] M. R. Bhalekar, A. R. Madgulkar, and G. J. Kadam. 2015. Evaluation of Gelling Agents for Clindamycin Phosphate Gel, World J. Pharm. Pharm. Sci., vol. 4, no. 07, p. 12.
[20] I. Tranggono and L. Fatma. 2007. Buku Pegangan Ilmu Pengetahuan Kosmetik. Jakarta: PT Gramedia Pustaka Utama.
[21] M. S. Che Zain, S. Y. Lee, N. M. Nasir, S. Fakurazi, and K. Shaari. 2010 Metabolite Characterization and Correlations with Antioxidant and Wound Healing Properties of Oil Palm (Elaeis guineensis Jacq.) Leaflets via 1H-NMR-Based Metabolomics Approach, Molecules, vol. 25, no. 23, p. 5636, doi: 10.3390/molecules25235636.
[22] T. Prasertpol and W. Tiyaboonchai. 2020. Nanostructured lipid carriers: A novel hair protective product preventing hair damage and discoloration from UV radiation and thermal treatment, J. Photochem. Photobiol. B, vol. 204, p. 111769, doi: 10.1016/j.jphotobiol.2019.111769.
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Published
2022-12-31
How to Cite
Narsa, A. C. (2022). Formulation and Stability Tests of Hair Tonic from Oil Palm (Elaeis guineensis Jacq.) Leaves Extract and Effectiveness in Protecting Hair. Journal of Tropical Pharmacy and Chemistry, 6(2), 144–153. https://doi.org/10.25026/jtpc.v6i2.524
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