Preliminary Phytochemical Screening and Quantitative Analysis of Methanol Leaf Extract of Erlangea tomentosa (Oliv. & Hiern) S.Moore (Asteraceae)

Authors

  • Anselme Mboneye Kampala International University, Department of Pharmacology and Toxicology; National Institute for Public Health, Department of Paraclinical Sciences
  • Albert Nyanchoka Onchweri Department of Pharmacology and Toxicology, Kampala International University, Western-Campus, Uganda
  • Timothy Neeza Department of Pharmacology and Toxicology, Kampala International University, Western-Campus, Uganda
  • Saidi Odoma Department of Pharmacology and Therapeutics, College of Health Sciences, Kogi State University, Anyigba, Nigeria

DOI:

https://doi.org/10.25026/jtpc.v7i1.528

Keywords:

Phytochemical screening, Quantitative analysis, Erlangea tomentosa, UV/Spectrophotometer, Methanol leaf extract.

Abstract

Various medications are being developed using natural products, particularly those resulting from medicinal plants. So, the screening and quantity analysis of phytochemicals in the methanol leaf extract of Erlangea tomentosa was looked at to find out what chemicals in the plant were responsible for its biological activity. Ten different phytochemicals, such as alkaloids, glycosides, cardiac glycosides, flavonoids, saponins, coumarins, steroids, terpenoids, phenols, and tannins, were found by the analysis. Glycosides and cardiac glycosides were below the limits, and neither phlobatannins nor anthraquinones were found. Quantitative phytochemical analysis showed that there were 3.38g of alkaloids, 2.19g of tannins, 1.81g of flavonoids, and 0.31g of saponins. The concentrations of standard solutions per 100g of crude sample were used to estimate all the results of the tests.

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References

Reis NC, Arantes BM, Menezes FPS, Leandro CL, De Souza PM, Pereira ML, Curcino VIJ, Oliveira D. 2020. Plants as sources of anti-inflammatory agents. Journal of Molecules; 25(3726): 1-22.

Lamara R, Andama M, Olet EA. 2020. Phytochemical composition of aqueous crude extracts of selected pesticidal plants used against Brassica vegetable pests. International Journal of Current Microbiology and Applied Sciences; 9(1): 468-478.

Micheni NK, Joseph MN, James MM. 2015. Pharmacological and toxicological effects of selected medicinal plants traditionally used to treat malaria in Msambweni sub-county, Kenya. University of Nairobi; 1(52): 1-117.

Isaac M, Samuel BO, Ivan I, Pender GC, Adam MA & Saidi O. 2020. Antinociceptive and anti-inflammatory activities of the aqueous leaf extract of Erlangea tomentosa (Asteraceae) in rats and mice. Journal of Pharmacy & Bioresources; 17(1):19-23.

Savina A. 2015. Nutri-medicinal plants used in the management of HIV / AIDS opportunistic infections in western Uganda: documentation, phytochemistry and bioactivity evaluation. TRITA-CHE Report; 2015 (34):1-81.

Berhan B, Bharat M, Asegedech T, Zewdneh S. 2017. Methanol leaves extract Hibiscus micranthus Linn exhibited antibacterial and wound healing activities. BMC Complementary and Alternative Medicine; 17(337): 1-11.

Porwal M, Ali KN, Kamal KM. 2017. Evaluation of acute and subacute oral toxicity induced by ethanolic extract of Marsdenia tenacissima leaves in experimental rats. Scientia Pharmaceutica; 85 (3):1-11.

Evans WC. 2009. Trease and Evans’ Pharmacognosy: Sixteenth Edition, 1–603.

Roghini R, Vijayalakshmi K. 2018. Phytochemical screening, quantitative analysis of flavonoids andminerals in ethanolic extract of Citrus paradisi. International Journal of Pharmaceutical Sciences and Research; 9(11): 4859-4864.

Roland OA, Ebenezer AM, Samuel AO. 2017. Qualitative and quantitave evaluation of the phytochemicals in dry, wet and oil extracts of the leaf of Morinda lucida. Journal of Biology, Agriculture, and Healthcare; 7(7): 22-25.

Madhu M, Sailaja V, Satyadev T, Satyanarayana MV. 2016. Quantitative phytochemical analysis of selected medicinal plant species by using various organic solvents. Journal of Pharmacognosy and Phytochemistry; 5(2):25-29.

Selvakumar S, Vimalanban S, Balakrishnan G. 2019. Quantitative determination of phytochemical constituents from Anisomeles malabarica. MOJ Bioequivalence & Bioavailability; 6(1): 19-21.

Khanal S. 2021. Qualitative and quantitative phytochemical screening of Azadirachta indica Juss. plant parts. International Journal of Applied Sciences and Biotechnology; 9(2): 122-127.

Longbap BD, Ushie OA, Ogah E, Kendenson AC, Nyikyaa JT. 2018. Phytochemical screening and quantitative determination of phytochemicals in leaf extracts of Hannoa undulata. International Journal of Medicinal Plants and Natural Products; 4(2): 32-38.

Bassiouni W, Daabees T, Louedec L, Norel X, Senbel A. 2019. Evaluation of some prostaglandins modulators on rat Corpus cavernosum in-vitro: Is relaxation negatively affected by COX-inhibitors? Biomedicine and Pharmacotherapy; 111(2019):1458-1466.

Ferraz CR, Carvalho TT, Manchope MF, Artero NA, Oliveira RFS, Fattori V, Casagrande R, Verri WA. 2020. Therapeutic potential of flavonoids in pain and inflammation: Mechanisms of action, pre-clinical and clinical data, and pharmaceutical development. In Molecules; 25(762): 1-35

Smeriglio A, Barreca D, Bellocco E, Trombetta D. 2017. Proanthocyanidins and hydrolysable tannins: occurrence, dietary intake and pharmacological effects. British Journal of Pharmacology; 174(11):1244-1262.

Gupta A, Chaphalkar SR. 2016. Terpenoids from three medicinal plants and their potential anti-inflammatory and immunosuppressive activity on Human whole blood and peripheral blood. Asian Journal of Ethnopharmacology and Medicinal Foods; 02(1):13-17.

Jesch ED, Carr TP. 2017. Food ingredients that inhibit cholesterol absorption. Preventive Nutrition and Food Science; 22(2): 67-80.

Martín FM, Tamayo VÁ, Aller R, Gonzalo BH, Martínez PP, Tamayo E. 2021. Endothelial dysfunction and neutrophil degranulation as central events in sepsis physiopathology. International Journal of Molecular Sciences; 22(12): 1-15.

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Published

2023-03-06

How to Cite

Mboneye, A., Onchweri, A. N., Neeza, T., & Odoma, S. (2023). Preliminary Phytochemical Screening and Quantitative Analysis of Methanol Leaf Extract of Erlangea tomentosa (Oliv. & Hiern) S.Moore (Asteraceae). Journal of Tropical Pharmacy and Chemistry, 7(1), 24–32. https://doi.org/10.25026/jtpc.v7i1.528

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